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The silent-film comic was a flop in the 13-minute Making a Living. But only a few days later, he'd introduce his iconic Little Tramp character — and take the first step toward immortality.

According to state and local authorities, 22 people in Western Pennsylvania have died of heroin overdose in less than two weeks. The wave of deaths is due to the appearance of an especially potent batch of heroin, mixed with the painkiller Fentanyl. NPR's Arun Rath speaks with Dr. Neil Capretto, medical director of the Gateway Rehabilitation Center in Pittsburgh.

The legendary Harlem nightclub and the artists and music it's synonymous with are being celebrated in a new Broadway revue. Jeff Lunden talks to cast members and the creators about the pleasures and perils of paying homage to a place with a problematic history.

A Jordanian woman brought her camel's milk skin-care line — and a biotech startup — to Missouri. Her company is studying how the long-acting antibodies in camel's milk can help clear up acne.

Sports medicine doctors say they've seen a rise in overuse injuries among kids who train long and hard.

Despite the enormous cost of hosting the Olympics, many former venues are languishing away unused.

Over the weekend, New Orleans Mayor Mitch Landrieu won a triumphant re-election victory. Even with the major progress New Orleans has made since Hurricane Katrina hit in 2005, there are plenty of challenges for Landrieu to tackle in a second term, including high rates of unemployment and crime.

Passenger pigeons went. Dodos went. Buffalo nearly went. But here's the surprise. Three of the weediest, everywhere-ist animals we know (the common pigeon, the white-tailed deer and Canada geese) — they almost went too! Everything, it turns out, is fragile.

The new League of Extraordinary Gentlemen book pits Captain Nemo's daughter against dark forces in a silent-film inspired Berlin. Reviewer Etelka Lehoczky says Nemo: Roses of Berlin is uneven but fun.

Isra al-Modallal is the first woman to be the public face of Hamas, the conservative group that rules the Palestinian territory. "Brilliant" is how one Gaza observer describes the decision.